My goodness – as usual, all kinds of confusion about this supplement (not to worry, the confusion is as old as the two forms). Yup, niacin is needed to reduce cholesterol but niacin produces the “flush”. Niacinamide doesn’t
diddly for cholesterol, but it doesn’t produce a flush. It is useful for other things, like diabetes. Here’s a useful url that sort of untangles the whole mess. btw – as with any/all supplements, there can be drug interactions – good or bad. If using this supplement, please be sure to check out the drug interactions section for this supplement.
Dales Dr said the flushing is less w/perscription niacin. He also said it is the best thing for you, so try as hard as you can to deal with the flushing. He has Dale taking it all at once. some nights he is fine then the next night boom red as a beet and itching like crazy.
Hi Kate, I think I remember reading somewhere that taking niacin amide instead of plain old niacin eliminated flushing also and was as effective as niacin. Do you know if this is so? Love, Mary Claire
PF Co. recently began promoting a chewable type of Sildenafil in Mexico. It’s called Sildenafil Jet, and PF Co. claims it might also advertise it to other states within the developing world, or even the Usa.
Vardenafil, another erectile dysfunction drug, is currently sold as a pill in nine European nations and could arrive at American pharmacies when this month below the title Staxyn. That new kind of the drug, which dissolves and fizzes in seconds, is advertised in a pocketsize, midnightblack box for guys who like to have it discreetly, without water.
The 3rd drug for ed to make it to the market, Tadalafil (generic cialis 20mg), now eight years of age, is racing ahead of others due to two thoughts which have proven exceptionally popular: a regular pill plus a 36hour “weekender.” Tadalafil is projected to become the topselling of the three medicines on earth in 2013, passing Sildenafil.
The market for medicines to fix ed has passed $5 billion annually from sales to tens of millions of men. And it’s increasingly being driven by innovative programs to compete with the lowerpriced generics to the horizon.
“A newer item, more affordable, plus a fresh kind of getting it — all that may persuade more people to attempt it.”
Study is also under way in Brazil on a quicker-acting type of the medicines, which raise blood circulation by relaxing smooth-muscle cells. This kind would enter more directly, raising the blood circulation within 10 or 15-minutes and dissolving in a capillary – rich room underneath the tongue, as the present tablets enter the bloodstream indirectly through the stomach, intestines and liver. The investigation in Brazil includes generic Sildenafil, but PF Co. claims it’s not sponsoring the job.
Studies demonstrated most Mexican guys who used Sildenafil floor it up-to make it easier to consume or within the idea it could begin acting quicker.
In describing why the drug is being testmarketed in Mexico, Ms. O’Connor mentioned “patient preference, seen in marketing research.” At this stage, PF Co. doesn’t have strategies to create Sildenafil Jet to america, she said.
In The Usa, PF Co. is fighting to maintain low-cost generic competitors off the shelves annually from now, if the drug’s patent expires. The generic tablets would cost just a portion of the $10 or more that every tablet now charges.
Bayer, meanwhile, has launched the type of its Levitra drug in France, Austria, Hungary, Germany, Spain, Poland, Sweden, Denmark and UK, where it went on-sale in late March. The drug is known as Levitra ODT, for oro-dispersible tablets. It comes in a slim black bundle the size of the halfdozen piled credit cards, with four tablets on the card that falls out.
“It’s pocket friendly, unobtrusive and provides the product a lively edge over its opponents,” Thomas Proske, international brand manager for Levitra at Bayer Healthcare, said in a statement.
The exact tablet was approved within the U.S.
last June under the brand-name Staxyn.
It’ll be available in drugstores this month, based on Jess Macnaught, advertising executive with Burgopak Design and Packaging, the new black package that was designed by the London company. Merck and glaxoSmithKline have certified American rights from Bayer, however they declined to disclose if the drug could be introduced. This past year, they stated Staxyn would get to the market in 2010.
Worldwide sales of ed medications grew 6.9 percent this year, to about $5 billion, and 4.7 percent last year, based on the business data company IMS Health.
Doctor. Alukal of New-york University said he believed Staxyn might be sold for a considerably lower cost than what Levitra and other pills now cost, simply to take on a generic Sildenafil. No cost was revealed.
“I figure it might be less difficult to ingest, therefore it might enlarge its marketplace somewhat, however ultimately the larger problem will be price,” Doctor. Alukal stated. He said the companies, for whom he doesn’t consult, had discussed pricing, maybe to under $ 10 a tablet.
But for the time being, PF Co., the business that started it-all, is concentrating its attention on protecting brand integrity and the pricing power of Sildenafil.
Patrick Ford, a former F.B.I. agent who directs the firm’s safety operations in the Americas, says Sildenafil is one of the most counterfeited goods on earth.
PF Co. is also making use of its legal firepower against would-be generic competitors.
“Most if not all analysts presume the expiration of the drug upon expiration of the composition of matter patent.”
The regulation is intended to support pharmaceutical companies to analyze kids’s uses, frequently a challenging and unprofitable place.
In cases like this, what could be analyzed isn’t Sildenafil for kids, but Revatio, a formula of exactly the exact same compound, revatio, that is approved for pulmonary arterial hypertension, a perilous and rare illness affecting hundreds of kids within america. Mr. Jimeson said the business was working closely with the Federal Food and Drug Administration to talk about the pediatric studies of Revatio and the possibility for an extension to the chemical patent, which will also protect Sildenafil and its particular costs.
Many guys, although, have waited years to get a lowerpriced Sildenafil as well as next year their wish will come true.
Other investigators are examining new uses for Sildenafil that PF Co. says it’s not funding. Boston University is examining it for testosterone gel in men 40 to 70. Laboratorio Teuto Brasileiro, in Brazil, where in fact the patent expired this past year, has submitted a notice of intention to analyze it in a pill that dissolves under the tongue and has an impact in 10 minutes or so. PF Co. owns 40% of the laboratory but states it didn’t begin the analysis.
Eli Lilly, meanwhile, says it has no plans to use chewable or dissolvable or any kinds of its own Tadalafil pills, and why should it? Tadalafil sales have steadily improved since it was launched in 2003, to $1.7 billion last year, near Sildenafil’s $1.9 billion.
Based on the Food And Drug Administration, in certain cases these difficulties can continue well following the patient stops taking the drug.
In an on-line statement, the Food And Drug Administration wrote:
The FDA stresses that obvious informal links between Propecia/Proscar 5mg and sexual side effects haven’t been compellingly proven.
Details on these potential side effects ought to be described to patients, the FDA provides. When talking about the advantages and dangers of finasteride both prescribers and patients must be mindful of them.
In fiftynine of those instances, the difficulties continued for more than 90 days after the patients stopped taking their drug. There were 131 cases of ed and 68 of decreased sex-drive (libido) associated with Proscar (1992-2010).
Propecia and Proscar
Finasteride is contained by both drugs, the active component. Finasteride is a 5 alphareductase inhibitor.
Proscar (finasteride 5 milligrams) was FDA-APPROVED in 1992 for managing the symptoms associated with enlarged prostate (benign prostatic hyperplasia). It’s also approved for treating urinary retention (reducing risk), or the demand for surgery associated with benign prostatic hyperplasia. Propecia (finasteride 1 mg) was approved in 1997 from the Food And Drug Administration. It’s used entirely by guys for healing male pattern baldness.
Finpecia is created and marketed by Merck. Pamela Eisele, a representative for the business, said:
Merck believes that Propecia and Proscar are normally well tolerated and successful because of their respective suggested use if used prior to their approved labeling.”
The FDA highlighted:
“Only a small percent of guys using all these medicines have experienced a sexual adverse-event.”
Umm, Well, of course, Happy Birthdays, Beth and LaVondra! Many, many happy returns of the day. I always seem to be on the tail end of extending best birthday wishes. Sorry. I’m simply not sure where the SS birthday calendar is. Love, Mary Claire
It’s me, Whitegoose! It’s Squeaky. I knew all along that the “Queen Mother Whitegoose” was really your stepmother and not you. You are “Princess Cinderella Whitegoose,” as everyone knows. Only a finely honed intellect like
mine can keep the royals straight on the “SS Incredibable.” Mary Claire is simply not up to the task. She’s also insensitive, and she’s intent on starving me to death too! (Soon I may need more than morsels of bread to keep me going.) Love, Squeaky “
My sister returns today, and I’ll be heading back home late evening, so I may not get my computer back up until late tomorrow sometime. Mary Claire, I’m sorry the Member List (with birthdays) is no longer active. I didn’t have time to keep it up to date, and it is on my “To Do” list of New Year Resolutions!!! I am also hoping to get a Book Index on our bookstore (I think this was one of last year’s New Year resolutions also!
So, as the last hours of this year play out, here’s wishing All of You, Good Health, Happiness, Joy and Peace in 2002!
Candy, great to hear from you. Can I take your email address @home as the correct one, and delete the other one, which keeps bouncing. Denyp 169 is on no emails, can I delete this one? Denyp 141 is on individual emails. Is this the correct one? hotcouple84 – no emails. Tell me, is this correct? Welcome to sopranomarie (Daily Digest). Great to have you with us. Our group is around 160 members. I’m finding it a little hard to keep
track of you all.
please let me (or the other moderators) know whenever you change email adresses.
Hi all new members My name is Ed , I to am a stroke suvivor, from 9/9/99 I am left side weak (and a little lop sided,to ) Im a 64 year old male , residing alone (sometimes ) I live in central western Nevada, in the foot of the Sierra Mountains I am originally from NEW YORK CITY (a rather long story, A real Payton Place kinda of thing) I have experienced many types of obstacles, thrown at me by stroke, from depression to and including confusion My advice is two things, Dont ever give up and dont loose your sense of humor Sometimes easier said then done ,I know When your overcome with bitterness, remember you can catch more bees with honey than with vingar I am fond of telling those crabs that they are sweeter than sex,you can change that to candy , which works also I have a dog , Brandy , whos pedigree is pure precious, half golden lab and half Austrailian Heeler and spoiled to the umpth degree A little more background , I had went to school for 36 years at night seeking a degree ( so you see I am real persistant or real dumb ) I was 6 credits away from a degree in engineering when I stroked At first this was very frustrating , but in time I came to realize that there is more important things in life Like love and family and this dam computer I dont think I need to tell you that this is a great group, Whitegoose ( the
boss ) included (no Im not sucking up either) Welcome to our family
Ed aka Rassils